Showing the 2025 E-Class E350: EPA's E350 and E350 4matic (2.0 L, AWD or RWD). Recalls and complaints cover the whole model year. Every version
Owner complaints, recalls, fuel economy and safety ratings from public NHTSA and EPA data, updated Oct 17, 2026.
Fuel economy
27–28 mpgcombined; city 24–25, highway 33; the E350
Five years of fuel
$14,370–$14,910U.S. average; Ohio $13,540–$14,050 at local prices; the E350; fuel only, not other costs of owning it; 15,000 miles a year, at EIA fuel prices for the week of Oct 12, 2026
NHTSA overall safety rating
Not ratedNHTSA has no overall rating for this year
NHTSA's VIN data lists these trims for the 2025 E-Class. A trim's engine and numbers are shown as its own only where EPA names versions after the trim and no other version could be it; "seen with" means a source shows that engine on the trim, not that it was the only one. Recalls and complaints cover the whole model year: whether a recall applies to a car depends on its VIN, on NHTSA's recall lookup.
Owners have filed 6 complaints with NHTSA about the 2025 E-Class. These are unverified owner reports, counted by the part of the car they name; one complaint can name several parts. Counts aren't adjusted for how many were sold, so they don't show how reliable a car is.
Complaints by part of the car
Part
Complaints
Crashes
Fires
Injuries
Electrical system
3
0
0
0
Unknown or other
2
0
0
0
Engine
1
0
0
0
Service brakes
1
0
0
0
Steering
1
0
0
0
Suspension
1
0
0
0
Visibility/wiper
1
0
0
0
Complaints by model year
Newer years have had less time to collect complaints, and counts aren't adjusted for sales, so a shorter bar doesn't mean a more reliable year.
NHTSA lists 2 recall campaigns for the 2025 E-Class over its history. Campaigns are matched by model and year, so each one may apply to a given car, and its repair may already be done: check a VIN on NHTSA's recall lookup for the open recalls on that exact car.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024-2026 AMG GT, C-Class, E-Class, SL, CLE, and GLC vehicles. The infotainment control unit may reset while the vehicle is in motion and cause the instrument panel display to go blank.
Risk: An instrument panel display that fails to show critical safety information, such as the speedometer and warning lights, increases the risk of a crash.
Remedy: Dealers will update the infotainment control unit software, free of charge. Owner notification letters were mailed June 29, 2026. MBUSA's number for this recall is 2026050004. Owners may contact MBUSA customer service at 1-800-367-6372. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning May 8, 2026.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2025 E 350, E 350 4MATIC, E 450 4MATIC, and E450 4MATIC station wagon vehicles. The camber strut bracket may have been improperly welded onto the rear axle carrier, possibly resulting in separation of the bracket from the rear axle carrier.
Risk: Rear axle carrier failure can cause a sudden loss of vehicle handling and control, increasing the risk of a crash.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will replace the rear axle carrier, free of charge. Owner notification letters were mailed January 22, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024120015.
Carmakers sent NHTSA 184 service bulletins and notices that cover the 2025 E-Class, the latest on Sep 26, 2026. They tell dealers how to fix known issues.
The parts they mention most: electrical system (94), structure (18), exterior lighting (15), suspension (15), power train (14).
NHTSA hasn't opened a defect investigation that covers this model year.
Maintenance
Oil
The owner's manual gives the oil and how often to change it. We show oil facts only once we've checked them against the manual, and we haven't yet for the 2025 E-Class.
See used 2025 Mercedes-Benz E-Classs for sale on: Autotrader · CarMax
These are searches on those sites; we don't copy or check their listings. Your ZIP is used for these links and never kept.
Specs
EPA class: midsize cars. EPA greenhouse gas score: 5–9 out of 10. Each version EPA tested:
Swipe the table sideways for more columns.
Version
Engine
Transmission
Fuel
City / hwy / comb
AMG E53 Hybrid 4matic Plus All-Wheel Drive
3.0 L, 6 cyl, turbo
Automatic 9-spd
Premium Gasoline or Electricity 43 miles on electricity, 410 miles in all
21 / 26 / 23 on gasoline 59 MPGe on electricity
E350 Rear-Wheel Drive
2.0 L, 4 cyl, turbo
Automatic 9-spd
Premium Gasoline
25 / 33 / 28
E350 4matic All-Wheel Drive
2.0 L, 4 cyl, turbo
Automatic 9-spd
Premium Gasoline
24 / 33 / 27
E450 4matic All-Wheel Drive
3.0 L, 6 cyl, turbo, supercharged
Automatic 9-spd
Premium Gasoline
22 / 31 / 25
E450 4matic All-Terrain All-Wheel Drive
3.0 L, 6 cyl, turbo, supercharged
Automatic 9-spd
Premium Gasoline
22 / 31 / 25
Sources and dates
U.S. EPA fuel economy data, file of Sep 29, 2026
NHTSA owner complaints, file of Oct 17, 2026
NHTSA recalls, file of Oct 17, 2026
NHTSA manufacturer communications, file of Oct 17, 2026
NHTSA defect investigations, file of Oct 17, 2026
NHTSA 5-Star Safety Ratings, file of Aug 7, 2026
U.S. Energy Information Administration, file of Oct 12, 2026
Fuel cost: EPA mpg with fuel prices for the week of Oct 12, 2026 and electricity prices for Jul 2026. Source: U.S. Energy Information Administration (Oct 2026). Complaints are unverified reports owners filed with NHTSA. About the data