Showing the 2021 GLS-Class GLS580-4M. NHTSA's VIN data shows it with a 4.0 L engine, but that may not be every version of it, so the numbers below cover every version of this model year. Every version
Owner complaints, recalls, fuel economy and safety ratings from public NHTSA and EPA data, updated Oct 18, 2026.
Fuel economy
16–21 mpgcombined; city 14–20, highway 18–24; every version of this model year
Five years of fuel
$19,160–$25,150U.S. average; Ohio $18,060–$23,700 at local prices; every version of this model year; fuel only, not other costs of owning it; 15,000 miles a year, at EIA fuel prices for the week of Oct 12, 2026
NHTSA overall safety rating
Not ratedNHTSA has no overall rating for this year
NHTSA's VIN data lists these trims for the 2021 GLS-Class. A trim's engine and numbers are shown as its own only where EPA names versions after the trim and no other version could be it; "seen with" means a source shows that engine on the trim, not that it was the only one. Recalls and complaints cover the whole model year: whether a recall applies to a car depends on its VIN, on NHTSA's recall lookup.
Owners have filed 37 complaints with NHTSA about the 2021 GLS-Class. These are unverified owner reports, counted by the part of the car they name; one complaint can name several parts. Counts aren't adjusted for how many were sold, so they don't show how reliable a car is.
Complaints by part of the car
Part
Complaints
Crashes
Fires
Injuries
Electrical system
17
0
2
1
Unknown or other
8
1
0
1
Engine
5
0
0
1
Forward collision avoidance
3
0
0
0
Lane departure
3
0
0
0
Fuel system, gasoline
2
0
0
0
Seats
2
0
2
0
Visibility/wiper
2
0
0
0
Air bags
1
1
0
1
Power train
1
0
0
0
Seat belts
1
0
0
0
Structure
1
0
0
0
4 more parts
Suspension
1
0
0
0
Tires
1
0
0
0
Vehicle speed control
1
0
0
0
Wheels
1
0
0
0
What the columns count
Complaints: complaints that name that part. One complaint can name several parts, so the rows overlap and don't add up to the total.
Crashes and Fires: complaints that report one. Two owners can file about the same event, and NHTSA doesn't link them, so these count reports, not events.
Injuries: the number of people the complaints say were injured.
None of these columns shows that a part caused a crash, fire or injury: they're what owners reported, unverified.
Complaints by model year
Newer years have had less time to collect complaints, and counts aren't adjusted for sales, so a shorter bar doesn't mean a more reliable year.
NHTSA lists 12 recall campaigns for the 2021 GLS-Class over its history. Campaigns are matched by model and year, so each one may apply to a given car, and its repair may already be done: check a VIN on NHTSA's recall lookup for the open recalls on that exact car.
Electrical system: wiring
NHTSA campaign 24V207000 · reported Mar 15, 2024 · 116,020 vehicles potentially affected across the whole campaign
Remedy: Dealers will inspect and tighten the 48-Volt ground connection as necessary, free of charge. Owner notification letters were mailed on May 3, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024040002.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023-2024 GLE 350, 2020-2024 GLE 450, 2020-2023 GLS 580, GLE 580, 2019-2023 GLS 450, 2021-2023 Maybach GLS 600, AMG GLS 63, 2021-2024 AMG GLE 53, AMG GLE 53 Coupe, and AMG GLE 63 S vehicles. A 48-Volt ground connection under the passenger seat may not be secured properly, resulting in the ground connection overheating.
Risk: An overheated ground connection can increase the risk of a fire.
NHTSA campaign 24V118000 · reported Feb 16, 2024 · 105,071 vehicles potentially affected across the whole campaign
Remedy: Dealers will update the transmission control unit software, free of charge. Owner notification letters were mailed March 29, 2024. Owners may contact MBUSA customer service at 1-800-367-6372.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2023 GLE 450 and GLS 450 vehicles. The transmission may not fully downshift in certain conditions, causing the engine to stall.
Risk: An engine stall increases the risk of a crash.
NHTSA campaign 23V445000 · reported Jun 26, 2023 · 143,551 vehicles potentially affected across the whole campaign
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
NHTSA campaign 23V177000 · reported Mar 17, 2023 · 61,450 vehicles potentially affected across the whole campaign
Remedy: Dealers will inspect and reinstall the air conditioner drain hoses, as necessary, free of charge. Owner notification letters were mailed April 28, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of recall numbers 21V-288 and 19V-587. MBUSA's numbers for this recall are 2023030014 and 15.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2021 GLE350, GLE450, GLS450, GLS580, 2021 AMG GLE53, AMG GLE63, Maybach GLS600, AMG GLS63, and 2020 GLE580 vehicles. The air conditioner drain hoses may have been incorrectly installed, causing water to drain into the passenger compartment.
Risk: Water intrusion into the foot wells may cause corrosion and/or short circuits to electrical components, increasing the risk of fire. In addition, the emergency call (eCall) feature may be disabled and the doors may not unlock, increasing the risk of injury. Also, the engine may not start or may enter a limp-home mode, increasing the risk of a crash.
NHTSA campaign 22V732000 · reported Sep 30, 2022 · 59,574 vehicles potentially affected across the whole campaign
Remedy: Dealers will inspect and replace the third-row seatback, as necessary, free of charge. Owner notification letters were mailed November 18, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100011.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 AMG GLS63, 2020-2022 GLS450 and GLS580 vehicles. Due to a manufacturing error, the locks on the third-row seatbacks may fail in the event of a crash.
Risk: A seat with a seatback lock failure may not properly restrain occupants, increasing the risk of injury during a crash.
NHTSA campaign 22V680000 · reported Sep 12, 2022 · 161,000 vehicles potentially affected across the whole campaign
Remedy: Dealers will inspect and secure the rear window trim bars, as necessary, free of charge. Owner notification letters were mailed November 1, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022090010.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE350, GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, and 2021 GLE400e, AMG GLS63, AMG GLE63 S, and Maybach GLS600 vehicles. Due to a manufacturing error, the rear door window trim bars may detach.
Risk: Detached trim bars may cause a road hazard and increase the risk of a crash or injury.
Communication: auto crash notification; Electrical system: software
NHTSA campaign 22V365000 · reported May 20, 2022 · 242,722 vehicles potentially affected across the whole campaign
Remedy: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
Risk: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
NHTSA campaign 22V231000 · reported Apr 8, 2022 · 21,306 vehicles potentially affected across the whole campaign
Remedy: Dealers will inspect and tighten the ground cable bolt, as necessary, free of charge. Owner notification letters were mailed July 8, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040017.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, 2021 AMG GLE63, Maybach GLS600 and AMG GLS63 vehicles. A ground cable bolt for the 48V ground connection under the front passenger seat may not be secured properly, which can cause the electrical cable to overheat.
Risk: An overheated electrical cable can increase the risk of a fire.
NHTSA campaign 21V832000 · reported Oct 22, 2021 · 23 vehicles potentially affected across the whole campaign
Remedy: Dealers will replace the rear window, free of charge. Owner notification letters were mailed December 8, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 GLE 350, GLE 580, GLS 450, GLS 580, AMG GLE 53, AMG GLE 63 S, and AMG GLS 63 S vehicles. The rear window may be insufficiently bonded to the tailgate, which could allow the rear glass to detach.
Risk: Detached rear glass can become a road hazard, increasing the risk of a crash.
Back over prevention: sensing system; Electrical system: software
NHTSA campaign 21V354000 · reported May 14, 2021 · 343,191 vehicles potentially affected across the whole campaign
Remedy: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."
Risk: A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.
Communication: auto crash notification; Electrical system: software
NHTSA campaign 21V058000 · reported Feb 5, 2021 · 1,292,258 vehicles potentially affected across the whole campaign
Remedy: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
NHTSA campaign 20V089000 · reported Feb 14, 2020 · 2,101 vehicles potentially affected across the whole campaign
Remedy: MBUSA will notify owners, and dealers will update the instrument cluster software, free of charge. The recall began March 31, 2020. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2020030019.
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2020 CLA250, CLA250 4MATIC and CLA35 AMG 4MATIC, 2020-2021 GLE350, GLE350 4MATIC, GLE450 4MATIC, GLS450 4MATIC and GLS580 4MATIC and 2021 GLE53 AMG Coupe, GLE63S AMG 4MATIC, GLS63 AMG 4MATIC and Maybach GLS600 4MATIC vehicles. The instrument cluster software may deactivate the illumination of certain interior switches (switch bar, overhead control unit, steering wheel) if the hazard lights are turned on and the ignition switch is in the 'off' position. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 101, "Control and Displays."
Risk: If the interior switches are not illuminated, they may be more difficult to find and operate, increasing the risk of a crash.
Carmakers sent NHTSA 325 service bulletins and notices that cover the 2021 GLS-Class, the latest on Sep 26, 2026. They tell dealers how to fix known issues.
The parts they mention most: electrical system (147), power train (35), visibility/wiper (28), engine (24), steering (21).
NHTSA hasn't opened a defect investigation that covers this model year.
Maintenance
Oil
The owner's manual gives the oil and how often to change it. We show oil facts only once we've checked them against the manual, and we haven't yet for the 2021 GLS-Class.
EPA class: standard sport utility vehicle. EPA greenhouse gas score: 2–4 out of 10. Each version EPA tested:
Swipe the table sideways for more columns.
Version
Engine
Transmission
Fuel
City / hwy / comb
AMG GLS63 4matic Plus 4-Wheel Drive
4.0 L, 8 cyl, turbo
Automatic 9-spd
Premium Gasoline
14 / 18 / 16
GLS450 4matic 4-Wheel Drive
3.0 L, 6 cyl, turbo
Automatic 9-spd
Premium Gasoline
20 / 24 / 21
GLS580 4matic 4-Wheel Drive
4.0 L, 8 cyl, turbo
Automatic 9-spd
Premium Gasoline
16 / 21 / 18
GLS600 4matic Maybach 4-Wheel Drive
4.0 L, 8 cyl, turbo
Automatic 9-spd
Premium Gasoline
15 / 19 / 16
Sources and dates
U.S. EPA fuel economy data, file of Sep 29, 2026
NHTSA owner complaints, file of Oct 18, 2026
NHTSA recalls, file of Oct 18, 2026
NHTSA manufacturer communications, file of Oct 18, 2026
NHTSA defect investigations, file of Oct 18, 2026
NHTSA 5-Star Safety Ratings, file of Aug 7, 2026
U.S. Energy Information Administration, file of Oct 12, 2026
Fuel cost: EPA mpg with fuel prices for the week of Oct 12, 2026 and electricity prices for Jul 2026. Source: U.S. Energy Information Administration (Oct 2026). Complaints are unverified reports owners filed with NHTSA. About the data