Showing the 2022 S-Class Mercedes-benz S600. NHTSA's VIN data shows it with a 6.0 L engine, but that may not be every version of it, so the numbers below cover every version of this model year. Every version
Owner complaints, recalls, fuel economy and safety ratings from public NHTSA and EPA data, updated Oct 18, 2026.
Fuel economy
15–24 mpgcombined; city 12–21, highway 21–30; every version of this model year
Five years of fuel
$16,770–$26,830U.S. average; Ohio $15,800–$25,280 at local prices; every version of this model year; fuel only, not other costs of owning it; 15,000 miles a year, at EIA fuel prices for the week of Oct 12, 2026
NHTSA overall safety rating
Not ratedNHTSA has no overall rating for this year
NHTSA's VIN data lists these trims for the 2022 S-Class. A trim's engine and numbers are shown as its own only where EPA names versions after the trim and no other version could be it; "seen with" means a source shows that engine on the trim, not that it was the only one. Recalls and complaints cover the whole model year: whether a recall applies to a car depends on its VIN, on NHTSA's recall lookup.
Owners have filed 46 complaints with NHTSA about the 2022 S-Class. These are unverified owner reports, counted by the part of the car they name; one complaint can name several parts. Counts aren't adjusted for how many were sold, so they don't show how reliable a car is.
Complaints by part of the car
Part
Complaints
Crashes
Fires
Injuries
Forward collision avoidance
16
0
1
0
Electrical system
11
0
1
0
Service brakes
9
0
0
0
Engine
7
0
1
0
Fuel system, gasoline
5
0
0
0
Power train
5
0
0
0
Tires
5
0
0
2
Structure
4
0
0
0
Suspension
3
0
0
0
Vehicle speed control
3
0
0
0
Wheels
3
0
0
0
Back over prevention
2
0
0
0
9 more parts
Engine and engine cooling
2
0
0
0
Unknown or other
2
0
0
0
Air bags
1
0
0
0
Communication
1
0
0
0
Exterior lighting
1
0
0
0
Seat belts
1
0
0
0
Steering
1
0
0
0
Visibility
1
0
0
0
Visibility/wiper
1
0
0
0
What the columns count
Complaints: complaints that name that part. One complaint can name several parts, so the rows overlap and don't add up to the total.
Crashes and Fires: complaints that report one. Two owners can file about the same event, and NHTSA doesn't link them, so these count reports, not events.
Injuries: the number of people the complaints say were injured.
None of these columns shows that a part caused a crash, fire or injury: they're what owners reported, unverified.
Complaints by model year
Newer years have had less time to collect complaints, and counts aren't adjusted for sales, so a shorter bar doesn't mean a more reliable year.
NHTSA lists 10 recall campaigns for the 2022 S-Class over its history. Campaigns are matched by model and year, so each one may apply to a given car, and its repair may already be done: check a VIN on NHTSA's recall lookup for the open recalls on that exact car.
Service brakes, hydraulic: foundation components
NHTSA campaign 26V638000 · reported Oct 2, 2026 · 30,064 vehicles potentially affected across the whole campaign
Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters are expected to be mailed November 27, 2026. Owners may contact MBUSA customer service at 1-800-367-6372. This recall expands previous NHTSA recall number 25V116. Vehicle Identification Numbers (VINs) involved in this recall became searchable on NHTSA.gov on October 9, 2026.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022-2025 S 500 4MATIC, Maybach S 580 4MATIC, Maybach S 680 4MATIC, S 580 4MATIC, 2023-2025 S 580 E 4MATIC, and 2024-2025 AMG S 63 E Performance vehicles. The front brake hoses may rupture and leak brake fluid.
Risk: A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.
NHTSA campaign 25V116000 · reported Feb 24, 2025 · 20,339 vehicles potentially affected across the whole campaign
Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2025030007.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.
Risk: A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.
NHTSA campaign 24V704000 · reported Sep 20, 2024 · 27,190 vehicles potentially affected across the whole campaign
Remedy: Dealers will update the ECU software, free of charge. Owner notification letters were mailed on November 15, 2024. Owner notification letters will be mailed in phases, on November 15, 2024, January 10, 2025, and February 21, 2025. Owners can contact Mercedes-Benz Customer Service at 1-877-496-3691. MBUSA's number for this recall is 2024100007.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 S580, and Maybach S580 vehicles. In the event of a mechanical failure in the engine Camtronic system, the engine control unit (ECU) software may cause the engine to overheat or stall.
Risk: An engine stall can increase the risk of a crash. In addition, an engine that overheats can increase the risk of a fire.
NHTSA campaign 23V880000 · reported Dec 21, 2023 · 79,676 vehicles potentially affected across the whole campaign
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
NHTSA campaign 23V445000 · reported Jun 26, 2023 · 143,551 vehicles potentially affected across the whole campaign
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
NHTSA campaign 22V935000 · reported Dec 16, 2022 · 1 vehicles potentially affected across the whole campaign
Remedy: Dealers will replace a portion of the dashboard, free of charge. The owner notification letter was mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023010001.
Mercedes-Benz USA, LLC (MBUSA) is recalling one 2022 S 500 vehicle. The dashboard may be insufficiently attached, which can result in an improper front passenger air bag deployment in the event of a crash.
Risk: Improper deployment of an air bag can increase the risk of injury.
Power train: axle assembly; Suspension: subframe/mounting bracket
NHTSA campaign 22V194000 · reported Mar 28, 2022 · 12 vehicles potentially affected across the whole campaign
Do not drive until repaired
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will inspect the sub frame weld on the rear axle carrier and replace the rear axle carrier as necessary, free of charge. Owner notification letters were mailed April 8, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for the recall is 2022030028.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 S580Z, S500V, and S580V vehicles. The sub frame weld for the thrust arm on the rear axle carrier may have been improperly welded, causing the thrust arm to break and detach.
Risk: A detached thrust arm can cause a sudden loss of vehicle control, or cause the vehicle to pull to one side during emergency braking, increasing the risk of a crash.
NHTSA campaign 22V189000 · reported Mar 25, 2022 · 8,396 vehicles potentially affected across the whole campaign
Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
Risk: Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
Communication: auto crash notification; Electrical system: software
NHTSA campaign 21V00J000 · reported Dec 27, 2021 · 1,239 vehicles potentially affected across the whole campaign
Remedy: The communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed February 23, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022010006.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS450, S500, and S580 vehicles. The communication module software may restrict or disable the emergency call system (eCall).
Risk: A disabled eCall system would prevent a vehicle occupant from contacting emergency services through the call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
NHTSA campaign 21V931000 · reported Nov 29, 2021 · 227 vehicles potentially affected across the whole campaign
Remedy: MBUSA has updated their computer server to correct the issue for most vehicles, free of charge. For vehicles that were not able to be updated remotely, dealers will provide the software update, free of charge. Owner notification letters were mailed January 25, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580, 2022 EQS450, EQS580, and S500 vehicles with an active and connected Mercedes me connect account. The MBUX infotainment system might allow activation of the television and internet display while driving, causing a distraction for the driver.
Risk: Driver distraction can increase the risk of a crash.
Carmakers sent NHTSA 342 service bulletins and notices that cover the 2022 S-Class, the latest on Sep 26, 2026. They tell dealers how to fix known issues.
The parts they mention most: electrical system (173), power train (34), structure (30), suspension (23), engine (22).
NHTSA hasn't opened a defect investigation that covers this model year.
Maintenance
Oil
The owner's manual gives the oil and how often to change it. We show oil facts only once we've checked them against the manual, and we haven't yet for the 2022 S-Class.
EPA class: large cars. EPA greenhouse gas score: 2–5 out of 10. Each version EPA tested:
Swipe the table sideways for more columns.
Version
Engine
Transmission
Fuel
City / hwy / comb
Maybach S680 4matic All-Wheel Drive
6.0 L, 12 cyl, turbo
Automatic 9-spd
Premium Gasoline
12 / 21 / 15
S500 4matic All-Wheel Drive
3.0 L, 6 cyl
Automatic 9-spd
Premium Gasoline
21 / 30 / 24
S580 4matic All-Wheel Drive
4.0 L, 8 cyl, turbo
Automatic 9-spd
Premium Gasoline
16 / 25 / 19
S580 4matic Maybach All-Wheel Drive
4.0 L, 8 cyl, turbo
Automatic 9-spd
Premium Gasoline
15 / 24 / 18
Sources and dates
U.S. EPA fuel economy data, file of Sep 29, 2026
NHTSA owner complaints, file of Oct 18, 2026
NHTSA recalls, file of Oct 18, 2026
NHTSA manufacturer communications, file of Oct 18, 2026
NHTSA defect investigations, file of Oct 18, 2026
NHTSA 5-Star Safety Ratings, file of Aug 7, 2026
U.S. Energy Information Administration, file of Oct 12, 2026
Fuel cost: EPA mpg with fuel prices for the week of Oct 12, 2026 and electricity prices for Jul 2026. Source: U.S. Energy Information Administration (Oct 2026). Complaints are unverified reports owners filed with NHTSA. About the data