Showing the 2021 Sienna XSE. NHTSA's VIN data shows it with a 2.5 L engine, but that may not be every version of it, so the numbers below cover every version of this model year. Every version
Owner complaints, recalls, fuel economy and safety ratings from public NHTSA and EPA data, updated Oct 17, 2026.
Fuel economy
35–36 mpgcombined; city 35–36, highway 36; every version of this model year
Five years of fuel
$9,020–$9,280U.S. average; Ohio $8,060–$8,290 at local prices; every version of this model year; fuel only, not other costs of owning it; 15,000 miles a year, at EIA fuel prices for the week of Oct 12, 2026
NHTSA's VIN data lists these trims for the 2021 Sienna. A trim's engine and numbers are shown as its own only where EPA names versions after the trim and no other version could be it; "seen with" means a source shows that engine on the trim, not that it was the only one. Recalls and complaints cover the whole model year: whether a recall applies to a car depends on its VIN, on NHTSA's recall lookup.
Owners have filed 210 complaints with NHTSA about the 2021 Sienna. These are unverified owner reports, counted by the part of the car they name; one complaint can name several parts. Counts aren't adjusted for how many were sold, so they don't show how reliable a car is.
Complaints by part of the car
Part
Complaints
Crashes
Fires
Injuries
Service brakes
88
8
0
2
Unknown or other
30
3
2
1
Air bags
29
2
0
5
Seats
22
1
0
3
Electrical system
17
1
1
1
Engine
11
0
2
0
Structure
11
0
0
1
Power train
10
2
0
0
Vehicle speed control
10
1
0
1
Seat belts
8
0
0
1
Forward collision avoidance
6
1
0
0
Fuel/propulsion system
6
0
0
0
12 more parts
Visibility/wiper
6
0
0
0
Visibility
5
0
0
0
Suspension
4
0
0
0
Exterior lighting
3
0
1
1
Lane departure
3
0
0
0
Steering
3
0
0
0
Tires
3
0
0
0
Back over prevention
2
0
0
0
Latches/locks/linkages
2
0
0
0
Chest clip, buckle, harness
1
0
0
0
Service brakes, hydraulic
1
0
0
0
Tether, lower anchor (ON CAR SEAT OR VEHICLE)
1
0
0
0
Complaints by model year
Newer years have had less time to collect complaints, and counts aren't adjusted for sales, so a shorter bar doesn't mean a more reliable year.
NHTSA lists 4 recall campaigns for the 2021 Sienna over its history. Campaigns are matched by model and year, so each one may apply to a given car, and its repair may already be done: check a VIN on NHTSA's recall lookup for the open recalls on that exact car.
Vantage Mobility, LLC (VM) is recalling certain 2021-2026 Honda Odyssey, 2021-2025 Chrysler Pacifica, and Toyota Sienna vehicles equipped with QRT-Deluxe and QRT-Max wheelchair restraints. The retractors may not lock, preventing the wheelchair from being properly secured.
Risk: An unsecured wheelchair can move during transit, increasing the risk of injury.
Remedy: Dealers will inspect and replace the retractors, free of charge. Owner notification letters was mailed January 27, 2026. Owners may contact Vantage Mobility customer service at 1-800-488-9082.
Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2021-2025 Sienna Hybrid vehicles. The bolts for the seatbacks on the third-row seat assemblies may not be tightened properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) numbers 202, "Head Restraints," 207, "Seating Systems," and 225, "Child Restraint Anchorage Systems."
Risk: An improperly tightened seatback may not adequately restrain the occupant during a crash, increasing their risk of injury.
Remedy: Dealers will tighten the seat assembly bolts, free of charge. Owner notification letters were mailed April 1, 2025. Owners may contact Toyota's customer service at 1-800-331-4331. Toyota's number for this recall is 25TA05.
Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2020-2021 Avalon, Avalon Hybrid, Corolla, Highlander, Highlander Hybrid, RAV4, RAV4 Hybrid, Lexus ES350, Lexus RX350, Lexus RX450H, 2021 Sienna Hybrid, Lexus ES250, 2020-2022 Camry, Camry Hybrid, and ES300H vehicles. A short circuit may develop in the Occupant Classification System (OCS) sensor, preventing the front passenger air bag from deploying.
Risk: An air bag that does not deploy during a crash increases the risk of injury.
Remedy: Dealers will inspect and replace the sensor as necessary, free of charge. Interim letters notifying owners of the safety risk were mailed in February 2024. Some final remedy owner letters were mailed October 31, 2024. Letters will continue to be mailed in phases through January 2026. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 23TB15/23TA15 Lexus 23LB03/23LA03.
Toyota Engineering & Manufacturing (Toyota) is recalling certain 2022 Lexus LX 600, Lexus NX 350h, Lexus NX 450h+, Toytoa RAV4 Hybrid, 2021-2022 Lexus LS 500h, Toyota Mirai, RAV4 PRIME, Sienna, Venza, and 2020-2022 Toyota Highlander Hybrid vehicles. The Skid Control ECU software may not turn on the Vehicle Stability Control (VSC) system when the vehicle is restarted after the driver has disabled the VSC system. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 126, "Electronic Stability Control Systems."
Risk: Driving with a deactivated stability control system increases the risk of a crash.
Remedy: Dealers will update the Skid Control ECU software, free of charge. Owner notification letters were mailed May 27, 2022. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 22TA03. Lexus' number for this recall is 22LA01.
Carmakers sent NHTSA 183 service bulletins and notices that cover the 2021 Sienna, the latest on Aug 20, 2026. They tell dealers how to fix known issues.
The parts they mention most: electrical system (58), equipment (38), structure (32), engine (28), engine and engine cooling (18).
NHTSA defect investigations
Opening an investigation isn't a finding of a defect. Outcomes are as NHTSA's summary states them. A recall is shown as an investigation's outcome only where NHTSA's summary names it; other recalls NHTSA's file lists with it are marked as listed, not caused.
Investigation
Part
Opened
Status
Defect petition DP22005 Pedestrian alert sounds · covers 43 makes
The owner's manual gives the oil and how often to change it. We show oil facts only once we've checked them against the manual, and we haven't yet for the 2021 Sienna.
EPA class: minivan. EPA greenhouse gas score: 7–8 out of 10. Each version EPA tested:
Swipe the table sideways for more columns.
Version
Engine
Transmission
Fuel
City / hwy / comb
Sienna Hybrid Front-Wheel Drive
2.5 L, 4 cyl
Automatic (AV-S6)
Regular Gasoline
36 / 36 / 36
Sienna Hybrid All-Wheel Drive
2.5 L, 4 cyl
Automatic (AV-S6)
Regular Gasoline
35 / 36 / 35
Sources and dates
U.S. EPA fuel economy data, file of Sep 29, 2026
NHTSA owner complaints, file of Oct 17, 2026
NHTSA recalls, file of Oct 17, 2026
NHTSA manufacturer communications, file of Oct 17, 2026
NHTSA defect investigations, file of Oct 17, 2026
NHTSA 5-Star Safety Ratings, file of Aug 7, 2026
U.S. Energy Information Administration, file of Oct 12, 2026
Fuel cost: EPA mpg with fuel prices for the week of Oct 12, 2026 and electricity prices for Jul 2026. Source: U.S. Energy Information Administration (Oct 2026). Complaints are unverified reports owners filed with NHTSA. About the data